Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
25 mg | 在庫あり | ¥ 7,500 | |||
50 mg | 在庫あり | ¥ 11,000 | |||
100 mg | 在庫あり | ¥ 16,000 | |||
500 mg | 在庫あり | ¥ 38,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS. |
In vivo | TRIM is a poor inhibitor of bovine aortic endothelial NOS with an IC50 of 1057.5 microM. TRIM (10-50 mg kg-1) administered i.p. exhibits dose-related antinociceptive activity in the mouse (assessed as inhibition of late phase formalin-induced hindpaw licking behaviour) with an ED50 of 85.8 mumol kg-1. In contrast, TRIM (50 mg kg-1, i.p.) failed to influence mean arterial blood pressure in the urethane-anaesthetized mouse[1]. |
別名 | 1-(2-Trifluoromethylphenyl)imidazole |
分子量 | 212.17 |
分子式 | C10H7F3N2 |
CAS No. | 25371-96-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.12 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TRIM 25371-96-4 Immunology/Inflammation NOS nNOS 1-(2-Trifluoromethylphenyl)imidazole eNOS Inhibitor inhibit anxiolytic-like effects NO Synthase Nitric oxide synthases iNOS antidepressant inhibitor