Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
説明 | LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1). |
ターゲット&IC50 | MTHFD2:663 nM (Ki), MTHFD1:18 nM (Ki), MTHFD1:IC50 : 96 nM |
分子量 | 471.42 |
分子式 | C20H21N7O7 |
CAS No. | 10538-99-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (127.28 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LY 345899 10538-99-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism DHFR LY-345899 inhibit Inhibitor LY345899 Methylenetetrahydrofolate Dehydrogenase (MTHFD) inhibitor