Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
2 mg | 在庫あり | ¥ 91,500 |
25 mg | 在庫あり | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity. |
ターゲット&IC50 | β3-adrenoceptor (human):2.4 nM (EC50) |
In vitro | LY377604 is a β1- and β2-adrenergic receptor antagonist as well as a β3-adrenergic receptor agonist, causing a maximal increase in cyclic adenosine monophosphate (cAMP) levels with an EC50 of 2.4 nM[1]. |
In vivo | LY377604 administered orally at 10mg/kg increases diet-induced obesity in male Long-Evans rats by enhancing calorie expenditure[1]. |
分子量 | 524.61 |
分子式 | C31H32N4O4 |
CAS No. | 204592-94-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (152.49 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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LY377604 204592-94-9 GPCR/G Protein Neuroscience Adrenergic Receptor LY-377604 LY 377604 Inhibitor inhibitor inhibit