store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin can be used for the treatment of benign prostatic hyperplasia.
ターゲット&IC50 | α2b-adrenoceptor:21 nM (Ki,Rat), 5-HT1A receptor:29 nM (Ki,Rat), α2A-adrenoceptor:92 nM (Ki,Human), α1B-adrenoceptor:24.9 nM (Ki), α2C-adrenoceptor:22 nM (Ki,Human), α1D-adrenoceptor:0.92 nM (Ki), α1A-adrenoceptor:0.16 nM (Ki) |
別名 | A 185980.1, ABT 980 |
分子量 | 555.65 |
分子式 | C30H29N5O4S |
CAS No. | 208993-54-8 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Fiduxosin 208993-54-8 GPCR/G Protein Neuroscience Adrenergic Receptor A 185980.1 ABT 980 Inhibitor inhibitor inhibit