Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MCH-1 antagonist 1 also inhibits CYP3A4 (IC50: 10μM).MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist (Ki: 2.6 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
ターゲット&IC50 | MCH1:2.6 nM (ki), CYP3A4:10 μM |
In vivo | The pharmacokinetic profile of MCH-1 antagonist 1 was assessed through its administration to male C57BL/6J DIO mice at a dosage of 30 mg/kg (po). This assessment focused on its impact on body weight, evidenced by an AUC0-6h of 14760 h*ng/mL. |
分子量 | 414.5 |
分子式 | C25H26N4O2 |
CAS No. | 1039825-68-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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MCH-1 antagonist 1 1039825-68-7 Metabolism P450 MCH1 antagonist 1 MCH 1 antagonist 1 Inhibitor inhibitor inhibit