Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes [1].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 20,500 | |||
25 mg | 在庫あり | ¥ 41,000 | |||
50 mg | 在庫あり | ¥ 66,500 | |||
100 mg | 在庫あり | ¥ 98,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 17,500 |
説明 | CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes [1]. |
ターゲット&IC50 | CYP1B1:0.2 nM, CYP1A1:3.98 μM |
In vitro |
CYP1B1-IN-4 (Compound 15) (1 nM-10 μM) inhibits CYP1A1 with an IC50 of 3.82 μM.[1] Cyp1b1-IN-4 (100 μM; 72 h) is non-cytotoxic to HEK293 cells.[1] |
分子量 | 322.38 |
分子式 | C18H14N2O2S |
CAS No. | 2685779-55-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32.24 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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CYP1B1-IN-4 2685779-55-7 Metabolism P450 Inhibitor inhibitor inhibit