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Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway.
説明 | Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway. |
In vitro | The active ingredient Neoprzewaquinone A (NEO) in crocetin selectively inhibits PIM1,a phenomenon observed at nanomolar concentrations. NEO effectively inhibits the PIM1 kinase and significantly suppresses the growth, migration, and epithelial-mesenchymal transition (EMT) of the triple-negative breast cancer cell line MDA-MB-231 in vitro [1]. |
分子量 | 556.6 |
分子式 | C36H28O6 |
CAS No. | 630057-39-5 |
keep away from direct sunlight,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Neoprzewaquinone A 630057-39-5 Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling JAK/STAT signaling Stem Cells Pim ROCK STAT Inhibitor inhibitor inhibit