store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in a guinea pig model of asthma.
説明 | RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in a guinea pig model of asthma. |
In vivo | In a dose-dependent fashion in guinea pigs, RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4. Similarly, RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction. At a dose of 10 mg/kg, RS-601 significantly inhibits the late-phase response and LPS-induced AHR. However, it does not affect biphasic bronchial responses. Additionally, RS-601 (3 and 10 mg/kg) clearly inhibits the AHR[1]. |
分子量 | 511.48 |
分子式 | C22H23F6NO4S |
CAS No. | 207987-59-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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RS-601 207987-59-5 GPCR/G Protein Proteases/Proteasome Thrombin Leukotriene Receptor RS601 RS 601 Inhibitor inhibitor inhibit