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カタログ番号	製品名	別名	ターゲット
T9845	Thrombin inhibitor 5
	Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor with IC 50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for venous thromboembolism research[1].
T7674	Thrombin Receptor Activator for Peptide		Protease-activated Receptor
	Thrombin Receptor Activator for Peptide is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).		Protease-activated Receptor
T19580	Thrombin (MW 37kDa)	Thrombin	Thrombin
	Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.		Thrombin
T10081	Thrombin inhibitor 1		Thrombin
	Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).		Thrombin
T7496	Thrombin Receptor Activator for Peptide 5 (TRAP-5)	Thrombin Receptor Activator for Peptide	Protease-activated Receptor
	Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research.		Protease-activated Receptor
T36777	Thrombin Receptor Agonist Peptide (trifluoroacetate salt)
	Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) ...
T17091	Thrombin Inhibitor 2		Others
	Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.		Others
T36553	Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
	Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating...
T7625	TRAP-6	PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)	Protease-activated Receptor
	TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).		Protease-activated Receptor
T72448	Thrombin inhibitor 6
	Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.
TP2234	Coagulation factor II (thrombin) B chain fragment [Homo sapiens]		Others
	Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser...		Others
T80512	Thrombin receptor peptide ligand		Thrombin
	Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].		Thrombin
T3757	NQ301		Thrombin , Platelet aggregation
	NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).		Thrombin , Platelet aggregation
T1986L	Atopaxar Hydrobromide		Protease-activated Receptor
	Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.		Protease-activated Receptor
T1986	Atopaxar	E5555,ER-172594-00	Protease-activated Receptor
	Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.		Protease-activated Receptor
T12870	SCH79797 dihydrochloride		Apoptosis , Others , Protease-activated Receptor
	SCH79797 dihydrochloride is a selective antagonist of nonpeptide protease activated receptor 1 (PAR1).		Apoptosis , Others , Protease-activated Receptor
T7137	I-191		Protease-activated Receptor
	I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.		Protease-activated Receptor
TQ0012	AZ3451		Protease-activated Receptor
	AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).		Protease-activated Receptor
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T6295	Dabigatran	BIBR 953,BIBR 953ZW	Thrombin
	Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients...		Thrombin
T2370	AC-55541	AOB2796	Proteasome , Protease-activated Receptor
	AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.		Proteasome , Protease-activated Receptor
T22246	Argatroban Monohydrate		Thrombin
	Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.		Thrombin
TP1046	SLIGRL-NH2	Protease-Activated Receptor-2 Activating Peptide	Protease-activated Receptor
	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.		Protease-activated Receptor
T6370	AEBSF hydrochloride	AEBSF HCl,Pefabloc SC	Thrombin , Serine Protease , Influenza Virus
	AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.		Thrombin , Serine Protease , Influenza Virus
T5519	Bivalirudin	BG-8967,Hirulog-1	Thrombin
	Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities.		Thrombin
T0155	Argatroban	MCI-9038,MD-805,Argipidine	Thrombin
			Thrombin
T0389	Dabigatran etexilate	BIBR 1048	Thrombin
	Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.		Thrombin
T7013	Vorapaxar	SCH 530348,MK-5348	Protease-activated Receptor
	Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).		Protease-activated Receptor
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T22323	Enoxaparin sodium		Thrombin
	Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu...		Thrombin
T5133	Dabigatran Etexilate Mesylate	BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin
	Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).		Thrombin
T17265	Ximelagatran	EXANTA,H 376-95,H37695,H 376/95,H-37695,H 37695	Thrombin
	Ximelagatran (H 376-95), a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the active agent melagatran in vivo.		Thrombin
T8917	PAR-2-IN-1	IUN76750	Protease-activated Receptor
	PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.		Protease-activated Receptor
T3098	Vorapaxar sulfate	SCH 530348 sulfate,Zontivity,vorapaxar monosulfate	Protease-activated Receptor
	Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.		Protease-activated Receptor
TP1065	PAR-4 Agonist Peptide, amide TFA	PAR-4-AP (TFA),AY-NH2 (TFA)	Protease-activated Receptor
	PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b...		Protease-activated Receptor
T10951	Dabigatran ethyl ester hydrochloride		Others , Thrombin
	Dabigatran ethyl ester hydrochloride is an effective inhibitor of ribosyl dihydronicotinic acid amide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and is a thrombin inhibitor.		Others , Thrombin
T7513	Protease-Activated Receptor-2, amide	SLIGKV-NH2	Protease-activated Receptor
	Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M)		Protease-activated Receptor
T7623	PAR-4 Agonist Peptide, amide	AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP	Protease-activated Receptor
	PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4).		Protease-activated Receptor
T2368	Edoxaban Tosylate Monohydrate	DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban	Factor Xa , Thrombin
	Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.		Factor Xa , Thrombin
T4186	AC-264613	AC264613	Protease-activated Receptor
	AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha...		Protease-activated Receptor
T40711	H-D-Phe-Pip-Arg-pNA dihydrochloride	S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride	Others
	H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thromb...		Others
T7573	TFLLR-NH2	TFLLR-NH2(2TFA)	Protease-activated Receptor
	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).		Protease-activated Receptor
T7380	Protease-Activated Receptor-4		Protease-activated Receptor
	Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy		Protease-activated Receptor
T22676	Prothrombin (474-477) [Mus musculus]		Others
	Prothrombin (coagulation factor II) is produced in the liver and is post-translationally modified in a vitamin K-dependent reaction that converts ten glutamic acids on prothrombin into gamma-carboxyglutamic acid. Prothro...		Others
T9892	JAMM protein inhibitor 2	Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-	Others
	JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin,...		Others
T36951	N-(p-Tosyl)-GPR-pNA acetate		Others
	N-(p-Tosyl)-GPR-pNA acetate is a colorimetric substrate for thrombin that can act as a measure of thrombin activity.		Others
T8362	Benzamidine hydrochloride	Benzamidine HCl	Serine/threonin kinase , Serine Protease
	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).		Serine/threonin kinase , Serine Protease
T25364L	Efegatran sulfate	LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate	Thrombin
	Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.		Thrombin
T9670L	Patamostat HCl	Patamostat HCl（114568-26-2 Free base）	Serine Protease , Protease
	Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50 values of 39 nM, 950 nM, and 1.9 μM, respectively.Patamosta...		Serine Protease , Protease
T8556	Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)	Z-Gly-Gly-Arg-AMC TFA	Others
	Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base) is a thrombin-specific fluorogenic substrate for testing thrombin generation in PRP and platelet-poor plasma (PPP).		Others

Compounds

Thrombin inhibitor 5

T9845

Synonym:

Target:

Thrombin Receptor Activator for Peptide

T7674

Synonym:

Target: Protease-activated Receptor

Thrombin (MW 37kDa)

T19580

Synonym: Thrombin

Target: Thrombin

Thrombin inhibitor 1

T10081

Synonym:

Target: Thrombin

Thrombin Receptor Activator for Peptide 5 (TRAP-5)

T7496

Synonym: Thrombin Receptor Activator for Peptide

Target: Protease-activated Receptor

Thrombin Receptor Agonist Peptide (trifluoroacetate salt)

T36777

Synonym:

Target:

Thrombin Inhibitor 2

T17091

Synonym:

Target: Others

Thrombin Receptor Peptide Ligand (trifluoroacetate salt)

Synonym: PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)

Target: Protease-activated Receptor

Thrombin inhibitor 6

T72448

Synonym:

Target:

coagulation factor II (thrombin) B chain fragment [Homo sapiens]

TP2234

Synonym:

Target: Others

Thrombin receptor peptide ligand

Target: Thrombin, Platelet aggregation

Atopaxar Hydrobromide

T1986L

Synonym:

Target: Protease-activated Receptor

Atopaxar

T1986

Synonym: E5555,ER-172594-00

Target: Protease-activated Receptor

SCH79797 dihydrochloride

T12870

Synonym:

Target: Apoptosis, Others, Protease-activated Receptor

I-191

T7137

Synonym:

Target: Protease-activated Receptor

AZ3451

TQ0012

Synonym:

Target: Protease-activated Receptor

MNS

T6594

Synonym:

Target: Syk, Src, p97

Dabigatran

T6295

Synonym: BIBR 953,BIBR 953ZW

Target: Proteasome, Protease-activated Receptor

Argatroban Monohydrate

Synonym: Protease-Activated Receptor-2 Activating Peptide

Target: Protease-activated Receptor

AEBSF hydrochloride

T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

Bivalirudin

T5519

Synonym: BG-8967,Hirulog-1

Target: Thrombin

Argatroban

T0155

Synonym: MCI-9038,MD-805,Argipidine

Synonym: SCH 530348,MK-5348

Target: Protease-activated Receptor

Parmodulin 2

T1893

Synonym: ML 161

Target: Protease-activated Receptor

Dabigatran Etexilate Mesylate

T5133

Synonym: BIBR 1048MS,Dabigatran etexilate methanesulfonate

Target: Thrombin

Ximelagatran

T17265

Synonym: EXANTA,H 376-95,H37695,H 376/95,H-37695,H 37695

Target: Protease-activated Receptor

Vorapaxar sulfate

T3098

Synonym: SCH 530348 sulfate,Zontivity,vorapaxar monosulfate

Target: Protease-activated Receptor

PAR-4 Agonist Peptide, amide TFA

TP1065

Synonym: PAR-4-AP (TFA),AY-NH2 (TFA)

Target: Protease-activated Receptor

Dabigatran ethyl ester hydrochloride

T10951

Synonym:

Target: Others, Thrombin

Protease-Activated Receptor-2, amide

T7513

Synonym: SLIGKV-NH2

Target: Protease-activated Receptor

PAR-4 Agonist Peptide, amide

T7623

Synonym: AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP

Target: Protease-activated Receptor

Edoxaban Tosylate Monohydrate

T2368

Synonym: DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban

Target: Factor Xa, Thrombin

AC-264613

T4186

Synonym: AC264613

Target: Protease-activated Receptor

H-D-Phe-Pip-Arg-pNA dihydrochloride

T40711

Synonym: S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride

Target: Others

TFLLR-NH2

T7573

Synonym: TFLLR-NH2(2TFA)

Target: Protease-activated Receptor

Protease-Activated Receptor-4

T7380

Synonym:

Target: Protease-activated Receptor

Prothrombin (474-477) [Mus musculus]

T22676

Synonym:

Target: Others

JAMM protein inhibitor 2

T9892

Synonym: Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-

Target: Others

N-(p-Tosyl)-GPR-pNA acetate

T36951

Synonym:

Target: Others

Benzamidine hydrochloride

T8362

Synonym: Benzamidine HCl

Target: Serine/threonin kinase, Serine Protease

Efegatran sulfate

T25364L

Synonym: LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate

Target: Thrombin

Patamostat HCl

T9670L

Synonym: Patamostat HCl（114568-26-2 Free base）

Target: Serine Protease, Protease

Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)

T8556

Synonym: Z-Gly-Gly-Arg-AMC TFA

Target: Others

カタログ番号	製品名	別名	ターゲット
T3839	Cycloolivil	Isoolivil	Free radical scavengers , Others , Platelet aggregation
	Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees. Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated t...		Free radical scavengers , Others , Platelet aggregation
TN1054	Loureirin C		Others
	Loureirin C can inhibit the activities of thrombin in vitro effectively.		Others
T3S0601	Buddlejasaponin IVb	Saikosaponin 1b	Others
	1. Buddlejasaponin IVb (Saikosaponin 1b)(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.		Others
T3781	Jujuboside B		Others
	Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.		Others
T3793	(20R)-Ginsenoside Rh1	20(R)-Ginsenoside Rh1	Others
	(20R)-Ginsenoside Rh1 (20(R)-Ginsenoside Rh1) can inhibit the thrombin-induced conversion of fibrinogen to fibrin.		Others
TN3831	(-)-Denudatin B	Denudatin B	ATPase , Potassium Channel , Calcium Channel , PAFR
			ATPase , Potassium Channel , Calcium Channel , PAFR
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
TN4917	Rosenonolactone		Others
	Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin.		Others
T36532	SCH 38519
	SCH 38519 is an isochromanequinone fungal metabolite originally isolated from Thermomonospora. It inhibits aggregation induced by thrombin , as well as inhibits serotonin secretion in human platelets (IC50s = 68 and 61 μ...
TN4860	Pueroside B		COX , PPAR
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece...		COX , PPAR
TN6014	Norcepharadione B
	Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human...

天然物製品

Cycloolivil

T3839

Synonym: Isoolivil

Target: Free radical scavengers, Others, Platelet aggregation

Synonym: Saikosaponin 1b

(20R)-Ginsenoside Rh1

T3793

Synonym: 20(R)-Ginsenoside Rh1

Target: ATPase, Potassium Channel, Calcium Channel, PAFR

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05025	Thrombin Receptor Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thrombin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is A0A024RAP7.
TMPY-04996	Coagulation Factor II Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.5 kDa and the accession number is A6HND0.
TMPY-01791	Coagulation Factor II Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Coagulation Factor II Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is P19221.
TMPH-00038	Thrombin-like enzyme contortrixobin Protein, Agkistrodon contortrix, Recombinant (His & Myc)	Agkistrodon contortrix	E. coli
	Thrombin-like snake venom serine protease that cleaves beta chain of fibrinogen (FGB), releasing fibrinopeptide B. Has a coagulant activity activating blood coagulation factors V (F5) and XIII (F13A1). Thrombin-like enzy...
TMPJ-00649	CPB2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the pl...
TMPJ-00243	Serpin B6 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in th...
TMPY-00916	Antithrombin III Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Antithrombin III Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa and the accession number is A0A024R944.
TMPH-01974	Prothrombin Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wo...
TMPH-01975	Prothrombin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Prothrombin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-02471	Antithrombin III Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Antithrombin III Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa.
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ...
TMPH-00768	SVTLE Protein, Gloydius ussuriensis, Recombinant (His & Myc)	Gloydius ussuriensis	E. coli
	Thrombin-like snake venom serine protease. Has a coagulant activity. Acts on alpha-chains of fibrinogen (FGA) generating fibrinopeptide A. SVTLE Protein, Gloydius ussuriensis, Recombinant (His & Myc) is expressed in E. c...
TMPH-01578	KRT18 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT...
TMPJ-00452	Serpin A1a Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elast...
TMPJ-00796	Serpin E2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
TMPH-00215	SVTLE Protein, Bothrops jararaca, Recombinant (His & Myc)	Bothrops jararaca	E. coli
	Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet aggregation through its interaction with GPIb (GP1BA/GP1BB), and ac...
TMPH-01577	KRT18 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPJ-01069	Serpin A1e Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPK-01044	VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPK-01043	VEGFC Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat...
TMPY-02242	Serpin B6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-...
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala...
TMPJ-01124	PDIA6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and br...
TMPY-03604	VAMP3 Protein, Human, Recombinant (His)	Human	E. coli
	VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components...
TMPJ-01282	Serpin B12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f...
TMPY-01718	Serpin B12 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-00707	Coagulation factor X/F10 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin ...
TMPJ-00505	Serpin A1 Protein, Human, Recombinant (aa 25-418, His)	Human	HEK293 Cells
	Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent,...
TMPJ-01083	Serpin E2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPJ-00301	Coagulation Factor X Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways a...
TMPJ-00193	TREML1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-...
TMPJ-00857	Thrombomodulin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a matu...
TMPJ-00734	KNG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kininogen-1 is a secreted protein which contains three cystatin domains. There are two alternatively spliced forms, designated as the high molecular weight (HMW) and low MW (LMW) forms. Kininogen-1 plays a critical role ...
TMPY-00821	HGFA Protein (pro form), Human, Recombinant (His)	Human	HEK293 Cells
	HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the act...
TMPJ-00535	F13A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, ...
TMPY-01840	TLT-1/TREML1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusive...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr...
TMPY-02014	Coagulation factor VII/F7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is...

Thrombin Receptor Protein, Human, Recombinant (His)

TMPY-05025

Species: Human

Expression System: HEK293 Cells

Coagulation Factor II Protein, Rat, Recombinant (His)

TMPY-04996

Species: Rat

Expression System: HEK293 Cells

Coagulation Factor II Protein, Mouse, Recombinant (His)

TMPY-01791

Species: Mouse

Expression System: HEK293 Cells

Thrombin-like enzyme contortrixobin Protein, Agkistrodon contortrix, Recombinant (His & Myc)

TMPH-00038

Species: Agkistrodon contortrix

Expression System: E. coli

CPB2 Protein, Human, Recombinant (His)

TMPJ-00649

Species: Human

Expression System: HEK293 Cells

Serpin B6 Protein, Human, Recombinant (E. coli, His)

TMPJ-00243

Species: Human

Expression System: E. coli

Antithrombin III Protein, Human, Recombinant (His)

TMPY-00916

Species: Human

Expression System: HEK293 Cells

Prothrombin Protein, Human, Recombinant (His)

TMPH-01974

Species: Human

Expression System: P. pastoris (Yeast)

Prothrombin Protein, Human, Recombinant (His & SUMO)

TMPH-01975

Species: Human

Expression System: E. coli

Antithrombin III Protein, Cynomolgus, Recombinant (His)

TMPY-02471

Species: Cynomolgus

Expression System: HEK293 Cells

Coagulation factor X/F10 Protein, Human, Recombinant (His)

TMPY-01101

Species: Human

Expression System: Baculovirus Insect Cells

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

TMPY-02185

Species: Human

Expression System: HEK293 Cells

SVTLE Protein, Gloydius ussuriensis, Recombinant (His & Myc)

TMPH-00768

Species: Gloydius ussuriensis

Expression System: E. coli

KRT18 Protein, Human, Recombinant (His)

TMPH-01578

Species: Human

Expression System: HEK293 Cells

Serpin A1a Protein, Mouse, Recombinant (His)

TMPJ-00452

Species: Mouse

Expression System: HEK293 Cells

Serpin E2 Protein, Human, Recombinant (His)

TMPJ-00796

Species: Human

Expression System: HEK293 Cells

SVTLE Protein, Bothrops jararaca, Recombinant (His & Myc)

TMPH-00215

Species: Bothrops jararaca

Expression System: E. coli

KRT18 Protein, Human, Recombinant (E. coli, His)

TMPH-01577

Species: Human

Expression System: E. coli

Serpin A5 Protein, Human, Recombinant (His)

TMPJ-00490

Species: Human

Expression System: HEK293 Cells

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

Serpin A1e Protein, Mouse, Recombinant (His)

TMPJ-01069

Species: Mouse

Expression System: HEK293 Cells

VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01044

Species: Human

Expression System: HEK293 Cells

VEGFC Protein, Human, Recombinant (His & Avi)

TMPK-01043

Species: Human

Expression System: HEK293 Cells

GPVI Protein, Mouse, Recombinant (His)

TMPJ-00605

Species: Mouse

Expression System: HEK293 Cells

Serpin B6 Protein, Human, Recombinant (His)

TMPY-02242

Species: Human

Expression System: Baculovirus Insect Cells

Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

TMPH-02778

Species: Mouse

Expression System: E. coli

PDIA6 Protein, Human, Recombinant (His)

TMPJ-01124

Species: Human

Expression System: HEK293 Cells

VAMP3 Protein, Human, Recombinant (His)

TMPY-03604

Species: Human

Expression System: E. coli

Serpin B12 Protein, Human, Recombinant (His)

TMPJ-01282

Species: Human

Expression System: HEK293 Cells

Serpin B12 Protein, Mouse, Recombinant (His)

TMPY-01718

Species: Mouse

Expression System: Baculovirus Insect Cells

Coagulation factor X/F10 Protein, Mouse, Recombinant (His)

TMPJ-00707

Species: Mouse

Expression System: HEK293 Cells

Serpin A1 Protein, Human, Recombinant (aa 25-418, His)

TMPJ-00505

Species: Human

Expression System: HEK293 Cells

Serpin E2 Protein, Mouse, Recombinant (His)

TMPJ-01083

Species: Mouse

Expression System: HEK293 Cells

Coagulation Factor X Protein, Human, Recombinant (hFc)

TMPJ-00301

Species: Human

Expression System: HEK293 Cells

TREML1 Protein, Human, Recombinant (hFc)

TMPJ-00193

Species: Human

Expression System: HEK293 Cells

Thrombomodulin Protein, Mouse, Recombinant (His)

TMPJ-00857

Species: Mouse

Expression System: HEK293 Cells

KNG1 Protein, Human, Recombinant (His)

TMPJ-00734

Species: Human

Expression System: HEK293 Cells

HGFA Protein (pro form), Human, Recombinant (His)

TMPY-00821

Species: Human

Expression System: HEK293 Cells

F13A Protein, Human, Recombinant (His)

TMPJ-00535

Species: Human

Expression System: HEK293 Cells

TLT-1/TREML1 Protein, Human, Recombinant (His)

TMPY-01840

Species: Human

Expression System: HEK293 Cells

Serpin A5 Protein, Mouse, Recombinant (His)

TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

Coagulation factor VII/F7 Protein, Human, Recombinant (His)

TMPY-02014

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L7500	Coagulation and Anticoagulation Compound Library		144 compounds
	A unique collection of 144 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Coagulation and Anticoagulation Compound Library

L7500

Compounds: 144