Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascular endothelial growth factor receptor 2-dependent phosphoinositide 3-kinase/Akt/mTOR/matrix metalloproteinase and p38 MAPK/matrix metalloproteinase pathways,two major pathways for tumor angiogenesis.
説明 | Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascular endothelial growth factor receptor 2-dependent phosphoinositide 3-kinase/Akt/mTOR/matrix metalloproteinase and p38 MAPK/matrix metalloproteinase pathways,two major pathways for tumor angiogenesis. |
植物由来 |
分子量 | 855.02 |
分子式 | C44H70O16 |
CAS No. | 88861-91-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Sprengerinin C 88861-91-0 Angiogenesis Apoptosis Cytoskeletal Signaling Immunology/Inflammation MAPK PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors mTOR p53 Akt PI3K ROS p38 MAPK VEGFR NADPH-oxidase Inhibitor inhibitor inhibit