Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively). TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 383,500 |
50 mg | 約6-8 週間 | ¥ 500,500 |
100 mg | 約6-8 週間 | ¥ 643,000 |
説明 | TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively). TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment. |
ターゲット&IC50 | MT1:0.081 nM (ki), MT2:0.042 nM (ki) |
別名 | PD-6735, LY-156735 |
分子量 | 280.75 |
分子式 | C14H17ClN2O2 |
CAS No. | 118702-11-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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TIK-301 118702-11-7 GPCR/G Protein Neuroscience 5-HT Receptor PD-6735 PD6735 LY156735 LY-156735 LY 156735 PD 6735 TIK301 TIK 301 Inhibitor inhibitor inhibit