Powder: -20°C for 3 years | In solvent: -80°C for 1 year
U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.
説明 | U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus. |
In vitro | U18666A, the antiviral effect is found to result from retarded viral trafficking in the cholesterol-loaded late endosomes/lysosomes and suppressed de novo sterol biosynthesis in treated infected cells. It is also observed an additive antiviral effect of U18666A with C75, a fatty acid synthase inhibitor [1][2]. |
分子量 | 424.06 |
分子式 | C25H42ClNO2 |
CAS No. | 3039-71-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (117.91 mM), Sonication is recommended.
H2O: 10 mg/mL (23.58 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
U18666A 3039-71-2 Microbiology/Virology Others Proteases/Proteasome HCV Protease inhibit U-18666A Inhibitor Hepatitis C virus HCV inhibitor