Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(E)-coumaroyloxyursolic acid exhibits antiplasmodial activity, with the IC50 value of 2.9 microg/ml.
説明 | Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(E)-coumaroyloxyursolic acid exhibits antiplasmodial activity, with the IC50 value of 2.9 microg/ml. |
植物由来 |
分子量 | 618.84 |
分子式 | C39H54O6 |
CAS No. | 277751-61-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Uncarinic acid E 277751-61-8 Apoptosis MAPK Microbiology/Virology PI3K/Akt/mTOR signaling Proteases/Proteasome MEK Caspase PI3K BCL Antifection p53 Inhibitor inhibitor inhibit