Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
説明 | Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively) |
ターゲット&IC50 | Piezo1 (human, Piezo1-transfected HEK293T cells):26.6 μM, Piezo1 (Piezo1-transfected HEK293T cells):17.1 μM |
In vitro | Yoda1 that acts as an agonist for both human and mouse Piezo1.?Functional studies in cells revealed that Yoda1 affects the sensitivity and the inactivation kinetics of mechanically induced responses[1]. |
分子量 | 355.27 |
分子式 | C13H8Cl2N4S2 |
CAS No. | 448947-81-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 28 mg/mL (80 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Yoda 1 448947-81-7 Membrane transporter/Ion channel Piezo Channel KcsA Potassium Channel Akt Yoda-1 PKB Inhibitor A431 cells HCAECs inhibit Protein kinase B ERK Piezo1 Extracellular signal regulated kinases Endothelial cells ERK1/2 Yoda1 inhibitor