Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellular system.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 107,000 | |||
10 mg | 在庫あり | ¥ 156,000 | |||
25 mg | 在庫あり | ¥ 245,500 | |||
50 mg | 在庫あり | ¥ 328,500 | |||
100 mg | 在庫あり | ¥ 443,000 |
説明 | (1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellular system. |
ターゲット&IC50 | GPR88 receptor:3 nM (EC50), Gαi-coupled pathway:56 nM |
In vitro | (1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay and 603 nM in cell assay[1][2]. In HEK293 cells stably expressing the human GPR88 receptor and the GloSensor-22F cAMP construct, (1R,2R)-2-PCCA inhibits GPR88-mediated cAMP production through a Gαi-coupled pathway, with an EC50 of 56 nM[2]. |
別名 | (1S,2R)-2-PCCA(Iso-1609563-71-4) |
分子量 | 528.56 |
分子式 | C30H39Cl2N3O |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (104.06 mM)
You can also refer to dose conversion for different animals. 詳細
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(1S,2R)-2-PCCA Endocrinology/Hormones GPCR/G Protein GPR 1609563-71-4-isomer 2-PCCA (1S,2R)-2-PCCA(Iso-1609563-71-4) Inhibitor inhibitor inhibit