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Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 49,000 |
5 mg | 在庫あり | ¥ 129,500 |
10 mg | 在庫あり | ¥ 203,500 |
25 mg | 在庫あり | ¥ 305,500 |
50 mg | 在庫あり | ¥ 408,500 |
100 mg | 在庫あり | ¥ 558,000 |
説明 | Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors. |
In vitro |
Inhibiting platelet aggregation induced by physiologic and pathologic agonists, abciximab (C7E3) achieves this effect by binding to the platelet αIIbβ3 integrin[2]. Abciximab appears to have similar affinity for the αIIbβ3 and αvβ3 integrins and redistributes between them[2]. |
In vivo | Effectively preventing neointimal hyperplasia, abciximab (C7E3) is administered at a dose of 0.25 mg/kg/day via intravenous infusion for 28 days[2]. |
別名 | C7E3 |
分子量 | N/A |
CAS No. | 143653-53-6 |
store at low temperature
store at -20°C
You can also refer to dose conversion for different animals. 詳細
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Abciximab 143653-53-6 Cytoskeletal Signaling Integrin C7E3 Inhibitor inhibitor inhibit