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Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be used to study relapsed/refractory multiple myeloma.
説明 | Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be used to study relapsed/refractory multiple myeloma. |
In vitro | Bersanlimab(BI-505) induces dose-dependent expression of ICAM-1 and programmed cell death (PCD) in Ramos, Raji, and Daudi lymphoma cells, with a dosage range spanning from 1 ng/mL to 1000 μg/mL [1]. |
In vivo | Bersanlimab (BI-505), administered at a dose of 20 mg/kg via intraperitoneal injection twice a week for a continuous period of 21 days, significantly reduces tumor growth and prolongs the survival of animals [1]. |
別名 | BI-505 |
分子量 | N/A |
CAS No. | 1987854-08-9 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
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Bersanlimab 1987854-08-9 Cytoskeletal Signaling Integrin BI-505 Inhibitor inhibitor inhibit