Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 101,000 | |||
10 mg | 在庫あり | ¥ 149,000 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
100 mg | 在庫あり | ¥ 429,500 |
説明 | AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing. |
ターゲット&IC50 | TRPML:< = 2 µM(AC50), TRPML1:< = 2 µM(AC50) |
In vitro | AKOS037652256 (Compound 8) (0.1-3 μM) was sufficient to induce TFEB-nuclear translocation (nuclear to cytosol ratio increased in a dose-dependent manner.[2] |
分子量 | 553.07 |
分子式 | C24H26ClFN4O4S2 |
CAS No. | 2171065-77-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.53 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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AKOS037652256 2171065-77-1 Inhibitor inhibitor inhibit