Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. This compound demonstrates strong efficacy in prostate cancer xenograft models [1].
説明 | Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. This compound demonstrates strong efficacy in prostate cancer xenograft models [1]. |
分子量 | 458.5 |
分子式 | C23H21F3N4OS |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Anticancer agent 135 Endocrinology/Hormones Androgen Receptor Inhibitor inhibitor inhibit