Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor Agent-92, an Icaritin derivative, induces G0/G1 phase cell cycle arrest and promotes apoptosis. This compound shows promise for hepatocellular carcinoma (HCC) research [1].
説明 | Antitumor Agent-92, an Icaritin derivative, induces G0/G1 phase cell cycle arrest and promotes apoptosis. This compound shows promise for hepatocellular carcinoma (HCC) research [1]. |
In vitro | Antitumor agent-92 (Compound 11c; 2-8 μM; 48 hours) induces apoptosis in HepG2 and SMMC-7721 cells, with increased effects at higher concentrations [1]. The compound also promotes G0/G1 phase arrest in these cells [1]. Additionally, Antitumor agent-92 upregulates P21 and downregulates Cdc2 p34 and CDK4 [1]. |
分子量 | 611.68 |
分子式 | C33H41NO10 |
CAS No. | 2922842-01-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Antitumor agent-92 2922842-01-9 Apoptosis Inhibitor inhibitor inhibit