Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CEP-28122 mesylate salt, a diaminopyrimidine derivative, serves as a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) inhibitor, exhibiting an IC 50 value of 1.9 nM against recombinant ALK kinase activity. It demonstrates antitumor efficacy in ALK-positive human cancer experimental models and possesses favorable pharmacodynamic and pharmacokinetic profiles.
説明 | CEP-28122 mesylate salt, a diaminopyrimidine derivative, serves as a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) inhibitor, exhibiting an IC 50 value of 1.9 nM against recombinant ALK kinase activity. It demonstrates antitumor efficacy in ALK-positive human cancer experimental models and possesses favorable pharmacodynamic and pharmacokinetic profiles. |
分子量 | 635.17 |
分子式 | C29H39ClN6O6S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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CEP-28122 mesylate salt Inhibitor inhibitor inhibit