store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clopidogrel thiolactone (2-oxoclopidogrel) is a potent P2Y12 receptor inhibitor and a potent antiplatelet aggregation compound.Clopidogrel thiolactone is the active metabolic intermediate resulting from the first oxidative activation of Clopidogrel.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
2 mg | 約 5 days | ¥ 40,000 |
5 mg | 約 5 days | ¥ 68,500 |
10 mg | 約 5 days | ¥ 108,000 |
1 mL * 10 mM (in DMSO) | 約 5 days | ¥ 75,000 |
説明 | Clopidogrel thiolactone (2-oxoclopidogrel) is a potent P2Y12 receptor inhibitor and a potent antiplatelet aggregation compound.Clopidogrel thiolactone is the active metabolic intermediate resulting from the first oxidative activation of Clopidogrel. |
In vivo | Clopidogrel thiolactone holds great promise as a more potent and a safer antiplatelet agent that might have the following advantages over clopidogrel: (1) no drug resistance for CYP2C19 poor metabolizers; (2) lower dose-related toxicity due to a much lower effective dose; (3) faster onset of action. Clopidogrel thiolactone (8 μm/kg; i.v.; Sprague-Dawley male rats) exhibits good biological availability and pharmacokinetic parameters[2]. |
別名 | 2-oxoclopidogrel |
分子量 | 337.82 |
分子式 | C16H16ClNO3S |
CAS No. | 1147350-75-1 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 2 mg/mL (5.92 mM), Sonication and heating are recommended.
DMSO: 30 mg/mL (88.80 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Clopidogrel thiolactone 1147350-75-1 GPCR/G Protein Neuroscience P2Y Receptor 2-oxoclopidogrel Inhibitor inhibitor inhibit