Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 9,000 | |||
10 mg | 在庫あり | ¥ 13,000 | |||
25 mg | 在庫あり | ¥ 21,000 | |||
50 mg | 在庫あり | ¥ 30,500 | |||
100 mg | お問い合わせ | ¥ 45,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome. |
ターゲット&IC50 | Platelet:1.8 μM. |
In vivo | Prasugrel significantly inhibits arterio-venous (AV) shunt and electrically induced arterial thrombosis in single dose ranges of 0.3 to 3 mg/kg and of 0.3 and 1 mg/kg/day for multiple doses. These doses are similar to doses with inhibition of platelet activation via P2Y12 receptors, suggesting that the protective effects of prasugrel in these cerebral infarction and peripheral arterial occlusive disease models reflect P2Y12 inhibitions on platelets by prasugrel's active metabolite. Prasugrel also significantly prevents progression of peripheral vascular lesions[1]. |
別名 | LY 640315, PCR 4099 (hydrochloride), Effient Hydrochloride, LY 640315 Hydrochloride, Prasugrel HCl |
分子量 | 409.9 |
分子式 | C20H20FNO3S·HCl |
CAS No. | 389574-19-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 43 mg/mL (104.9 mM)
Ethanol: 9 mg/mL (21.95 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Prasugrel Hydrochloride 389574-19-0 GPCR/G Protein Neuroscience P2Y Receptor LY640315 aggregation LY 640315 platelet Inhibitor PCR-4099 antiplatelet LY-640315 Hydrochloride ADP PCR 4099 active PCR4099 PCR 4099 (hydrochloride) metabolite LY640315 Hydrochloride inhibit Effient Hydrochloride LY-640315 Prasugrel LY 640315 Hydrochloride Prasugrel HCl inhibitor