Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Devapamil (Devapamilo) is a phenylalkylamine that blocks L-type calcium currents from the inner side of membrane cells in a use-dependent manner.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 18,500 | |||
5 mg | 在庫あり | ¥ 41,500 | |||
10 mg | 在庫あり | ¥ 60,000 | |||
25 mg | 在庫あり | ¥ 116,500 | |||
50 mg | 在庫あり | ¥ 156,000 | |||
100 mg | 在庫あり | ¥ 222,500 | |||
500 mg | 在庫あり | ¥ 443,000 |
説明 | Devapamil (Devapamilo) is a phenylalkylamine that blocks L-type calcium currents from the inner side of membrane cells in a use-dependent manner. |
In vitro | Devapamil (3 μM) reduced L-type calcium currents (ICa) to 16.1 +/- 8.6%, 11 +/- 8.9%, and 9.3 +/- 6% of control, respectively. Intracellular application of the same substances, via the patch pipette filled with 30 μM of devapamil, failed to depress ICa. The quaternary derivatives of the phenylalkylamines (30 microM) were ineffective both when applied extracellularly or intracellularly. It is suggested that phenylalkylamines block ICa in ventricular myocytes by acting on a binding site of the calcium channel molecule located at the outer surface of the cell membrane.[3] |
別名 | Devapamilo, Devapamilum |
分子量 | 424.58 |
分子式 | C26H36N2O3 |
CAS No. | 92302-55-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (117.76 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Devapamil 92302-55-1 Membrane transporter/Ion channel Metabolism Calcium Channel Devapamilo Devapamilum Inhibitor inhibitor inhibit