Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase, leading to mitotic disasters, polynuclearization, and loss of cancer cell dryness. FiVe1 selectively and irreversibly inhibit the growth of mesenchymal transformed breast cancer cells (FOXC2-HMLER cell, IC50=234nM) and soft tissue sarcomas of different histological subtypes.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 75,500 |
5 mg | 在庫あり | ¥ 183,500 |
10 mg | 在庫あり | ¥ 250,500 |
25 mg | 在庫あり | ¥ 379,000 |
50 mg | 在庫あり | ¥ 512,000 |
100 mg | 在庫あり | ¥ 672,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 216,500 |
説明 | FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase, leading to mitotic disasters, polynuclearization, and loss of cancer cell dryness. FiVe1 selectively and irreversibly inhibit the growth of mesenchymal transformed breast cancer cells (FOXC2-HMLER cell, IC50=234nM) and soft tissue sarcomas of different histological subtypes. |
分子量 | 359.25 |
分子式 | C18H16Cl2N4 |
CAS No. | 932359-76-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.59 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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FiVe1 932359-76-7 Others Inhibitor inhibitor inhibit