Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1]. |
ターゲット&IC50 | IDO1:0.64 μM |
In vitro | IDO1-IN-21, administered at concentrations ranging from 0 to 50 μM for 48 hours, inhibits the viability of SW480 cells, with an IC50 value of 28.64 μM [1]. At a lower concentration range of 0 to 10 μM over 48 hours, IDO1-IN-21 suppresses IDO1 activity in HeLa cells, with an IC50 value of 1.04 μM [1]. |
In vivo | IDO1-IN-21 (50, 100 mg/kg; i.p.; every three days for 21 consecutive days) inhibited tumor growth in CT26 tumor-bearing mice [1]. |
分子量 | 479.45 |
分子式 | C21H19F2N3O6S |
CAS No. | 2892432-98-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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IDO1-IN-21 2892432-98-1 Metabolism Indoleamine 2,3-Dioxygenase (IDO) Inhibitor inhibitor inhibit