Powder: -20°C for 3 years | In solvent: -80°C for 1 year
iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1]. |
ターゲット&IC50 | iNOS:0.065 μM, eNOS:>50 μM |
In vitro | iNOS inhibitor-10 at a concentration of 1 μM suppresses iNOS activity by 83% while remaining inactive against eNOS [1]. The same inhibitor, ranging from 0.001 to 100 μM over a period of 5 days, diminishes the viability of MDA-MB-231 cells [1]. Furthermore, at 25 μM for 24 hours, it impedes the migration of MDA-MB-231 cells [1]. Tested in liver microsomes, iNOS inhibitor-10 displays moderate metabolic stability, evidenced by a half-life (t1/2) of 38 minutes and an intrinsic clearance (CLint) of 39.6 mL/min/Kg [1]. |
分子量 | 393.5 |
分子式 | C22H23N3O2S |
CAS No. | 2918773-63-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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iNOS inhibitor-10 2918773-63-2 Immunology/Inflammation NO Synthase Inhibitor inhibitor inhibit