store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JY-2 is an orally active and selective forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity and inhibits FoxO1 transcription.JY-2 can be used to study psoriasis and diabetes.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 37,500 | |||
50 mg | 在庫あり | ¥ 57,000 | |||
100 mg | 在庫あり | ¥ 85,500 |
説明 | JY-2 is an orally active and selective forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity and inhibits FoxO1 transcription.JY-2 can be used to study psoriasis and diabetes. |
In vitro | JY-2, at concentrations ranging from 10 to 100 μM for 24 hours, reduces palmitic acid induced lipotoxicity in HepG2 and INS-1 cells [1]. |
In vivo | JY-2 exhibits anti-diabetic effects in mice, administered orally at doses of 50-200 mg/kg, either three times over two days or daily for 4 weeks [1]. |
分子量 | 292.12 |
分子式 | C13H7Cl2N3O |
CAS No. | 339103-05-8 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (273.86 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JY-2 339103-05-8 Apoptosis FOXO1 Inhibitor inhibitor inhibit