keep away from direct sunlight,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK-0159 is an orally available, highly potent CD38 inhibitor with myocardial injury protection for the study of cardiac ischemia and reperfusion injury.
説明 | MK-0159 is an orally available, highly potent CD38 inhibitor with myocardial injury protection for the study of cardiac ischemia and reperfusion injury. |
ターゲット&IC50 | CD38 (mouse):3 nM, CD38 (human):22±5 nM, CD38 (rat):70 nM |
In vitro | MK-0159 (0-50 μM, 24 hours) increased the levels of NAD+ both intracellularly and extracellularly in A549 cells and HMVEC cells[1]. |
In vivo | In mice with cardiac ischemia/reperfusion injury, MK-0159 (30 mg/kg; oral) is capable of reducing infarct size[1]. |
分子量 | 400.495 |
分子式 | C20H24N4O3S |
CAS No. | 2641484-61-7 |
keep away from direct sunlight,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (199.75 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MK-0159 2641484-61-7 Immunology/Inflammation CD38 Inhibitor inhibitor inhibit