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Search Results for " CD38 "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T14913	CD38 inhibitor 1		CD38
	CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.		CD38
T79732	CD38 inhibitor 3		CD38
	CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD+ content and Nrf2 expression. In a Pus1 -/- mouse model of ...		CD38
T61681	CD38 inhibitor 2
	CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).
T9918	Daratumumab		Others
	Daratumumab is a human monoclonal antibody that targets CD38 a cell surface protein that is overexpressed on multiple myeloma MM) cells.		Others
T24920	UCD38B HCl	UCD38B hydrochloride,UCD 38 B hydrochloride,UCD-38-B HCl,UCD-38-B Hydrochloride,UCD 38 B HCl
	UCD38B HCl is a cell-permeable intracellular uPA inhibitor that acts by killing proliferative and non-proliferative high-grade glioma cells by programmed necrosis.
T69940	NCD38
	NCD38 is a potent, selective LSD1 inhibitor.
T78577	NCD38 TFA		Histone Demethylase
	NCD38 TFA serves as a selective inhibitor of LSD1 [1] [2].		Histone Demethylase
T61933	MK-0159		CD38
	MK-0159 is an orally available, highly potent CD38 inhibitor with myocardial injury protection for the study of cardiac ischemia and reperfusion injury.		CD38
T60099	RBN013209		CD38
	RBN013209 is a potent CD38 inhibitor. RBN013209 is useful in the treatment of cancer.		CD38
T38951	Isatuximab	SAR-650984,hu38SB19,Isatuximab-irfc	Apoptosis , CD38
	Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has ...		Apoptosis , CD38
T77006	Felzartamab	TJ-202,MOR-03087,MOR-202	CD38
	Felzartamab(MOR-202) is a human-targeted monoclonal antibody to CD38 for the study of multiple myeloma and advanced antibody-mediated rejection of allogeneic kidney transplants.		CD38
T38730	Ara-F-NAD+
	Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.
T77084	Mezagitamab
	Mezagitamab (TAK-079), an IgG1λ anti-CD38 monoclonal antibody, functions by depleting tumor cells that express CD38 through both antibody and complement-dependent cytotoxicity. It shows potential for use in the treatment...
T82440	Erzotabart		CD38
	Erzotabart, an IgG1-kappa monoclonal antibody targeting CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1) in Homo sapiens, exhibits antineoplastic activity [1].		CD38
T37475	Cyclic ADP-Ribose (ammonium salt)	cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)
	Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second mes...
T77091	Modakafusp alfa
	Modakafusp alfa (TAK-573) is a humanized anti-CD38 IgG4 monoclonal antibody, with 2 attenuated IFNα2b molecules fused to it. This compound is researched for potential use in treating multiple myeloma [1].
T74032	Ara-F-NAD+ sodium
	Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].
T13907	Sulfo-ara-F-NMN	CZ-48	Others
	Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NM...		Others
T37803	8-bromo-Cyclic ADP-Ribose (sodium salt)
	Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, w...
T83798	8-bromo NAD+ sodium	8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+
	8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38. At a concentration of 1 mM, it effectively inhibits the rise in in...

Compounds

Synonym: UCD38B hydrochloride,UCD 38 B hydrochloride,UCD-38-B HCl,UCD-38-B Hydrochloride,UCD 38 B HCl

Target: Histone Demethylase

Synonym: SAR-650984,hu38SB19,Isatuximab-irfc

Target: Apoptosis, CD38

Felzartamab

T77006

Synonym: TJ-202,MOR-03087,MOR-202

Cyclic ADP-Ribose (ammonium salt)

T37475

Synonym: cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)

8-bromo-Cyclic ADP-Ribose (sodium salt)

Synonym: 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+

Target:

カタログ番号	製品名	ターゲット
TN1895	Luteolinidin chloride	CD38
	Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.	CD38
TN1513	Clitorin	PKC , Antifection
	Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.	PKC , Antifection

天然物製品

Luteolinidin chloride

Target: PKC, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01023	CD38 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03923	CD38 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05573	CD38 Protein, Human, Recombinant (His), PE conjugated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03721	CD38 Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03634	CD38 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-06651	CD38 Protein, Mouse, Recombinant	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03206	CD38 Protein, Rat, Recombinant (His)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03087	CD38 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01158	CD38 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05574	CD38 Protein, Human, Recombinant (His), FITC conjugated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05273	CD38 Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02776	CD38 Protein, Human, Recombinant (His & FLAG)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05606	CD38 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-06811	CD38 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00190	CD38 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicoti...
TMPJ-00202	CD157 Protein, Human, Recombinant (hFc)	Human	Human Cells
	The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow str...
TMPY-03037	CD157 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01178	CD157 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00968	CD157 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03038	CD157 Protein, Rat, Recombinant (His)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...