Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.
説明 | HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx. |
In vitro | HUP30 inhibits phenylephrine induced aortic contraction with an IC50 value of 3.9 μ M. HUP30 (100 μ M) increases cGMP levels in the aorta stimulated by adrenaline. HUP30 has an antispasmodic effect on the 25/30 mM K+constricted rat aortic ring, with an IC50 value of 7.5 μ M. HUP30 (3-100 μ M) inhibits phenylephrine induced extracellular Ca2+ influx and Ca2+ mobilization. HUP30 (10-100 μ M) inhibits current in single tailed artery muscle cells [1]. |
分子量 | 305.35 |
分子式 | C14H15N3O3S |
CAS No. | 312747-21-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.0 mg/mL (59.0 mM)
You can also refer to dose conversion for different animals. 詳細
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HUP30 312747-21-0 Membrane transporter/Ion channel Metabolism Potassium Channel Calcium Channel Inhibitor inhibitor inhibit