store at low temperature
store at -80°C
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway activation. It can inhibit the agglutinin pathway. Narsoplimab can be used to study diseases associated with hematopoietic stem cell transplantation in adults.
説明 | Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway activation. It can inhibit the agglutinin pathway. Narsoplimab can be used to study diseases associated with hematopoietic stem cell transplantation in adults. |
In vitro | Narsoplimab (100 nM; 3 h; Vero E6 cells and Vero E6 cells with SARS-CoV-2) inhibits N protein-enhanced MASP-2 deposition[1]. |
In vivo | Narsoplimab (10 mg/kg; i.v.; WT and Masp2-/- (KO) mice) reduced the percentage of lymphocytes (Lym%) and increased the percentage of neutrophils (Neu%)[1]. |
別名 | OMS 721 |
分子量 | N/A |
CAS No. | 2108782-45-0 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
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Narsoplimab 2108782-45-0 Microbiology/Virology SARS-CoV OMS 721 OMS721 OMS-721 Inhibitor inhibitor inhibit