Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
2 mg | 約8-10 週間 | ¥ 45,500 |
5 mg | 約8-10 週間 | ¥ 80,000 |
25 mg | 約8-10 週間 | ¥ 262,000 |
50 mg | 約8-10 週間 | ¥ 342,000 |
100 mg | 約8-10 週間 | ¥ 457,000 |
1 mL * 10 mM (in DMSO) | 約8-10 週間 | ¥ 88,000 |
説明 | p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM). |
ターゲット&IC50 | p38 MAPK:68 nM |
In vivo | p38 MAPK-IN-1 dose-dependently inhibits TNFα production (ED50: 0.5 mg/kg). p38 MAPK-IN-1 (1 mg/kg for iv and 10 mg/kg for p.o.) has a t1/2 of 7.4 hours and CL of 2.7 mL/min/kg for iv, and a Cmax of 5.3 μM for p.o. in male wistar rats[1]. |
分子量 | 348.35 |
分子式 | C21H14F2N2O |
CAS No. | 1006378-90-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8.33 mg/mL (23.84 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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