Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) has research value in schizophrenia.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 49,000 |
5 mg | 在庫あり | ¥ 123,500 |
10 mg | 在庫あり | ¥ 178,500 |
25 mg | 在庫あり | ¥ 271,000 |
50 mg | 在庫あり | ¥ 372,000 |
説明 | Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) has research value in schizophrenia. |
In vitro | Pomaglumetad methionil (LY2140023) is a high-affinity peptide transporter 1 (PEPT1) substrate with a Km value of ~30 µM. LY2140023 is active against [14C]Gly-Sar with an IC50 value of 0.018 mM[2]. |
In vivo | Pomaglumetad methionil (LY2140023; orally; 3-300 mg/kg; once daily for 7 days) dose-dependent increases the levels of the dopamine metabolites dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) [1]. |
別名 | LY2140023 hydrochloride |
分子量 | 402.87 |
分子式 | C12H19ClN2O7S2 |
CAS No. | 635318-26-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (55.8 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Pomaglumetad methionil hydrochloride 635318-26-2 Neuroscience GluR LY2140023 hydrochloride Pomaglumetad methionil Hydrochloride LY 2140023 Hydrochloride LY2140023 Hydrochloride LY-2140023 Hydrochloride Inhibitor inhibitor inhibit