Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 7,000 | |||
5 mg | 在庫あり | ¥ 16,000 | |||
10 mg | 在庫あり | ¥ 24,500 | |||
25 mg | 在庫あり | ¥ 59,500 | |||
50 mg | 在庫あり | ¥ 107,500 | |||
100 mg | 在庫あり | ¥ 157,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 27,000 |
説明 | Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype. |
In vitro | The study investigates the impact of selectively inhibiting Akt in proliferating cells that express Trop-2. In cells expressing Trop-2, Akt inhibition, whether achieved through silencing or specific drugs, significantly reduces cell proliferation in a dose-dependent manner.[1] |
In vivo | When Trop-2-expressing tumors are subcutaneously injected into animal models, they exhibit a remarkable reduction in growth upon treatment with specific drugs targeting Akt activity. This underscores the central functional role of Akt in mediating the Trop-2-dependent growth stimulus.[1] |
別名 | Rivanicline 2HCl(15585-43-0 Free base) |
分子量 | 235.15 |
分子式 | C10H16Cl2N2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (212.63 mM)
You can also refer to dose conversion for different animals. 詳細
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Rivanicline 2HCl Neuroscience AChR Rivanicline 2HCl(15585-43-0 Free base) Rivanicline Inhibitor inhibitor inhibit