Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells. It promotes cell death in MIA PaCa-2 by elevating intracellular ROS levels, diminishing mitochondrial membrane potential, and triggering apoptosis. This compound holds potential for cancer research [1].
説明 | SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells. It promotes cell death in MIA PaCa-2 by elevating intracellular ROS levels, diminishing mitochondrial membrane potential, and triggering apoptosis. This compound holds potential for cancer research [1]. |
分子量 | 443.88 |
分子式 | C23H22ClNO6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SB-1295 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species Inhibitor inhibitor inhibit