Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SIRT5 Inhibitor 5 is a potent substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 0.21 µM, and does not interact with the NAD+-binding pocket [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | SIRT5 Inhibitor 5 is a potent substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 0.21 µM, and does not interact with the NAD+-binding pocket [1]. |
ターゲット&IC50 | SIRT5:0.21 μM |
In vitro | SIRT5 inhibitor 5 (compound 47) (0-10 µM) exhibits consistent inhibitory activity across varying concentrations of NAD+ (50, 100, 200, 400, 800 µM) and shows reduced inhibitory potency with increasing concentrations of Ac-K(Suc)-AMC (10, 30, 90, 270 µM) [1]. |
分子量 | 423.87 |
分子式 | C21H14ClN3O3S |
CAS No. | 2883730-60-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SIRT5 inhibitor 5 2883730-60-5 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin Inhibitor inhibitor inhibit