Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 36,500 | |||
5 mg | 在庫あり | ¥ 91,000 | |||
10 mg | 在庫あり | ¥ 147,500 | |||
25 mg | 在庫あり | ¥ 228,000 | |||
50 mg | 在庫あり | ¥ 305,500 | |||
100 mg | 在庫あり | ¥ 408,500 | |||
500 mg | 在庫あり | ¥ 831,000 |
説明 | SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA). |
In vitro | SMN-C2 (20 mg/kg/day) used in Δ7 mice (a severe model of SMA) can substitute SMN2 splicing, causing an increase in SMN protein levels in the brains and spinal cords of mice, improving mouse motor function, and extending mouse lifespan[1]. |
分子量 | 417.5 |
分子式 | C24H27N5O2 |
CAS No. | 1446311-56-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SMN-C2 1446311-56-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis Inhibitor inhibitor inhibit