store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 67,500 |
2 mg | 在庫あり | ¥ 100,000 |
5 mg | 在庫あり | ¥ 166,000 |
10 mg | 在庫あり | ¥ 226,500 |
25 mg | 在庫あり | ¥ 349,000 |
50 mg | 在庫あり | ¥ 454,500 |
説明 | Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases. |
In vivo | In Ndufs4−/− mice (Leigh Disease model), Sonlicromanol hydrochloride (10 mg/kg; intraperitoneal injection, once daily) significantly improved rotarod and gait performance, reduced degeneration of retinal ganglion cells. Additionally, it resulted in significantly higher FA values in the external capsule and showed a similar trend in the cerebral peduncle[1]. |
別名 | KH 176 hydrochloride |
分子量 | 368.9 |
分子式 | C19H29ClN2O3 |
CAS No. | 2162149-24-6 |
store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (406.61 mM), Sonification is recommended.
H2O: 80 mg/mL (216.86 mM.)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Sonlicromanol hydrochloride 2162149-24-6 Immunology/Inflammation ROS KH 176 hydrochloride Inhibitor inhibitor inhibit