Powder: -20°C for 3 years | In solvent: -80°C for 1 year
THK-523 has shown selectivity and high affinity for tau pathology both in vitro and in vivo. 18 F-THK523 is a potent tau imaging radiotracer which is a potent in vivo tau imaging ligand for Alzheimer's disease [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | THK-523 has shown selectivity and high affinity for tau pathology both in vitro and in vivo. 18 F-THK523 is a potent tau imaging radiotracer which is a potent in vivo tau imaging ligand for Alzheimer's disease [1]. |
In vivo | THK-523 effectively penetrates the blood-brain barrier in mice, demonstrating an increased in vivo retention rate in the brains of Tau transgenic mice [1]. In this animal model, utilizing tau transgenic mice [1], the compound was administered intravenously at a dosage of 0.35 μg/kg, with observations made 25-30 minutes post-administration. The result noted was an overexpression of Tau in the brain. |
分子量 | 282.31 |
分子式 | C17H15FN2O |
CAS No. | 1573029-17-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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THK-523 1573029-17-0 Inhibitor inhibitor inhibit