Powder: -20°C for 3 years | In solvent: -80°C for 1 year
W1131 TFA is a potent STAT3 inhibitor inducing ferroptosis, effectively halting cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. Besides mitigating chemoresistance to 5-FU in cancer cells, it modulates the cell cycle, DNA damage response, and oxidative phosphorylation, targeting pathways such as IL6-JAK-STAT3 and ferroptosis [1].
説明 | W1131 TFA is a potent STAT3 inhibitor inducing ferroptosis, effectively halting cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. Besides mitigating chemoresistance to 5-FU in cancer cells, it modulates the cell cycle, DNA damage response, and oxidative phosphorylation, targeting pathways such as IL6-JAK-STAT3 and ferroptosis [1]. |
分子量 | N/A |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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W1131 TFA JAK/STAT signaling Stem Cells STAT Inhibitor inhibitor inhibit