store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Z-LEHD-FMK is a selective and potent caspase-9 inhibitor that protects against reperfusion injury and slows apoptosis.Z-LEHD-FMK exhibits antitumor and neuroprotective activity, increases the yield of in vitro-produced preimplantation embryos of Bubalus bubalis and alters the cellular stress response.
パッケージサイズ | 在庫状況 | 単価(税別) | |
---|---|---|---|
1 mg | 在庫あり | ¥ 48,500 | |
5 mg | 在庫あり | ¥ 170,500 | |
10 mg | 在庫あり | お問い合わせ | |
25 mg | 在庫あり | お問い合わせ | |
50 mg | 在庫あり | お問い合わせ | |
100 mg | 在庫あり | お問い合わせ |
説明 | Z-LEHD-FMK is a selective and potent caspase-9 inhibitor that protects against reperfusion injury and slows apoptosis.Z-LEHD-FMK exhibits antitumor and neuroprotective activity, increases the yield of in vitro-produced preimplantation embryos of Bubalus bubalis and alters the cellular stress response. |
In vitro | Pretreated for 30 minutes at a concentration of 20 μM, Z-LEHD-FMK completely protects HCT116 and 293 cells from TRAIL-induced toxicity[1]. Additionally, at a concentration of 20 μM for 6 hours, Z-LEHD-FMK protects normal human hepatocytes from TRAIL-induced apoptosis[1]. |
In vivo | In spinal cord injury (SCI) rats, Z-LEHD-FMK administered intravenously at a dose of 0.8 μmol/kg for 7 days protects neurons, glia, myelin, axons, and intracellular organelles[3]. |
分子量 | 690.72 |
分子式 | C32H43FN6O10 |
CAS No. | 210345-04-3 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (130.30 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Z-LEHD-fmk 210345-04-3 Apoptosis Proteases/Proteasome Caspase ZLEHDFMK Z LEHD FMK Inhibitor inhibitor inhibit