B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. In mammals, B cells mature in the bone marrow. B cell activation occurs in the secondary lymphoid organs (SLOs), such as the spleen and lymph nodes. After B cells mature in the bone marrow, they migrate through the blood to SLOs, which receive a constant supply of antigen through circulating lymph. At the SLO, B cell activation begins when the B cell binds to an antigen via its B-cell receptors (BCR).
Immature B cells express CD19, CD20, CD34, CD38, and CD45R. Most mature B cells express IgM, CD19, CD20, and CD22. Activated B cells express CD30. Plasma B cells could not express CD19, but could express CD78.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPY-00158 | Siglec-2/CD22 Protein, Rat, Recombinant (hFc)
Siglec-2/CD22 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-00037 | B7-1 Protein, Rat, Recombinant (hFc)
B7-1 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ... | |||
TMPY-00036 | CD28 Protein, Cynomolgus, Recombinant (hFc)
CD28 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | HEK293 |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ... | |||
TMPY-00004 | CD28 Protein, Rat, Recombinant (hFc)
CD28 Protein, Rat, Recombinant (hFc)
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Rat | HEK293 |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ... | |||
TMPY-00002 | CD37 Protein, Mouse, Recombinant (hFc)
CD37 Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 |
CD37 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 43.6 kDa. Accession number: Q4FK35 | |||
TMPK-01334 | EMMPRIN/CD147 Protein, Canine, Recombinant (His)
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulati... | |||
TMPK-01318 | CD24 Protein-VLP, Cynomolgus, Recombinant
CD24 Protein-VLP, Cynomolgus, Recombinant
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Cynomolgus | HEK293 |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil pr... | |||
TMPK-01310 | Syndecan-1 Protein, Rabbit, Recombinant (His)
Syndecan-1 Protein, Rabbit, Recombinant (His)
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Rabbit | HEK293 |
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix int... | |||
TMPK-01284 | Syndecan-1 Protein, Cynomolgus, Recombinant (His)
Syndecan-1 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog... | |||
TMPK-01278 | CD69 Protein, Cynomolgus, Recombinant (His)
CD69 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 |
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymp... | |||
TMPK-01270 | CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
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Cynomolgus,Rhesus macaque | HEK293 |
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD11... | |||
TMPK-01202 | CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
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Human | HEK293 |
CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM... | |||
TMPK-01177 | CD28 Protein, Canine, Recombinant (mFc)
CD28 Protein, Canine, Recombinant (mFc)
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Canine | HEK293 |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-01176 | CD28 Protein, Canine, Recombinant (His)
CD28 Protein, Canine, Recombinant (His)
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Canine | HEK293 |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc)
B7-2 Protein, Human, Recombinant (hFc)
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Human | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi)
B7-2 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00842 | CD21 Protein, Human, Recombinant (His)
CD21 Protein, Human, Recombinant (His)
|
Human | HEK293 |
CD21 mRNA expression, an EBV-entry receptor, was transiently detected in NK cells after exosome treatment, and levels decreased after further culture. CD21 prote... | |||
TMPK-00840 | CD21 Protein, Mouse, Recombinant (His)
CD21 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 |
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and... | |||
TMPK-00809 | CD37 Protein, Human, Recombinant (His)
CD37 Protein, Human, Recombinant (His)
|
Human | HEK293 |
CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymp... |