Chemokines are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines have been classified into four main subfamilies: CXC, CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPJ-00028 | CCL2 Protein, Mouse, Recombinant
CCL2 Protein, Mouse, Recombinant
|
Mouse | E. coli |
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence,... | |||
TMPJ-00019 | CCL28 Protein, Human, Recombinant
CCL28 Protein, Human, Recombinant
|
Human | E. coli |
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD... | |||
TMPJ-00018 | CCL16 Protein, Human, Recombinant
CCL16 Protein, Human, Recombinant
|
Human | E. coli |
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 a... | |||
TMPJ-00012 | CXCL4 Protein, Human, Recombinant (His)
CXCL4 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-bindi... | |||
TMPJ-00011 | CXCL2 Protein, Mouse, Recombinant
CXCL2 Protein, Mouse, Recombinant
|
Mouse | E. coli |
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted ... | |||
TMPJ-00010 | CCL8 Protein, Human, Recombinant
CCL8 Protein, Human, Recombinant
|
Human | E. coli |
CCL8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12 KDa and the accession number is P80075. | |||
TMPJ-00009 | CCL2 Protein, Human, Recombinant
CCL2 Protein, Human, Recombinant
|
Human | E. coli |
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine t... | |||
TMPJ-00008 | CXCL10 Protein, Human, Recombinant (hFc & His)
CXCL10 Protein, Human, Recombinant (hFc & His)
|
Human | HEK293 Cells |
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in re... | |||
TMPJ-00006 | CXCL1 Protein, Mouse, Recombinant (His)
CXCL1 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fib... | |||
TMPJ-00005 | CCL3 Protein, Human, Recombinant
CCL3 Protein, Human, Recombinant
|
Human | E. coli |
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocy... |