Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death-allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons.
Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPJ-00086 | CT-1 Protein, Human, Recombinant (His)
CT-1 Protein, Human, Recombinant (His)
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Human | E. coli |
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate ... | |||
TMPJ-00081 | CNTF Protein, Human, Recombinant
CNTF Protein, Human, Recombinant
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Human | E. coli |
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor ax... | |||
TMPJ-00024 | GMF beta/GMFB Protein, Human, Recombinant (His)
GMF beta/GMFB Protein, Human, Recombinant (His)
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Human | E. coli |
Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor... |