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PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

カタログ番号 TMPK-00502
別名: PDI5, HL-60, PAD, PADI5, Protein-arginine deiminase type-4, HL60 PAD, PAD4, HL-60 PAD

Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 76.6 kDa and the accession number is A0A2K5USI5.

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PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 241,000
500 μg 約5 days ¥ 964,000
1 mg 約5 days ¥ 1,604,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 76.6 kDa and the accession number is A0A2K5USI5.
Species Cynomolgus
Expression Host E. coli
Tag N-His
Accession Number A0A2K5USI5
別名 PDI5, HL-60, PAD, PADI5, Protein-arginine deiminase type-4, HL60 PAD, PAD4, HL-60 PAD
Construction Met1-Pro663
Protein Purity > 95% as determined by Tris-Bis PAGE
分子量 76.6 kDa (predicted) same as Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 10% Glycerol, 0.5 mM TCEP, 1 mM EDTA (pH 8.0).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.

参考文献

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Keywords

PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated PAD 4 PDI5 PDI-5 HL-60 PAD PADI5 PDI 5 PADI 5 Protein-arginine deiminase type-4 HL60 HL 60 HL60 PAD PAD4 PAD-4 PADI-5 HL-60 PAD recombinant recombinant-proteins proteins protein