ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.
説明 | ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95. |
Species | Human |
Expression Host | E. coli |
Tag | N-His |
Accession Number | A0A024RC95 |
別名 | ALDH6, aldehyde dehydrogenase 1 family, member A3, ALDH1A6, RALDH3, MCOP8 |
Construction | The Human ALDH1A3 (NP_000684.2) (Ala 2-Pro 512) was expressed, with a polyhistide tag at the N-terminus. |
Protein Purity | > 96 % as determined by SDS-PAGE |
分子量 | 57 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Supplied as sterile PBS 7.4 10% glycerol 0.2% TWEEN20. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism. |
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Please read the User Guide of Recombinant Proteins for more specific information.
ALDH1A3 Protein, Human, Recombinant (His) ALDH 6 ALDH6 ALDH-6 MCOP 8 aldehyde dehydrogenase 1 family, member A3 RALDH-3 ALDH1A6 RALDH3 MCOP8 RALDH 3 MCOP-8 recombinant recombinant-proteins proteins protein