Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XE991 is a novel and selective Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current, and can be used for the study of neurological diseases.
説明 | XE991 is a novel and selective Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current, and can be used for the study of neurological diseases. |
ターゲット&IC50 | [3H] acetylcholine:490 nM |
In vitro | XE991 and DMP 543 have EC50 values of 490 nM and 700 nM, respectively, for enhancing [3H] acetylcholine release from rat brain slices[2]. |
分子量 | 376.45 |
分子式 | C26H20N2O |
CAS No. | 122955-42-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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XE991 122955-42-4 Membrane transporter/Ion channel Potassium Channel Inhibitor inhibitor inhibit