Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
50 μg | 在庫あり | ¥ 88,500 |
100 μg | 約5 days | ¥ 156,500 |
200 μg | 約5 days | ¥ 275,500 |
500 μg | 約5 days | ¥ 583,000 |
生物学的情報 | Testing in progress |
説明 | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
Species | Human |
Expression Host | P. pastoris (Yeast) |
Tag | C-His |
Accession Number | AAH09647.1 |
別名 | ALPI, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, IAP, ALP |
Construction | Human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity |
> 80 % as determined by SDS-PAGE
|
分子量 | 54.1 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20% glycerol, pH 7.5. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) ALPI PLAP1 PLAP 1 PALP PLAP PLAP-1 alkaline phosphatase, placental IAP ALP recombinant recombinant-proteins proteins protein