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CDH17 Domain 7 Protein, Human, Recombinant (hFc)

カタログ番号 TMPK-00949
別名: CDH16, P130, MGC142024, Cdh17, FLJ26931, Cadherin-17, MGC138218, cadherin-16, HPT-1, LI-cadherin, BILL-cadherin

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 139,000
500 μg 約5 days ¥ 555,500
1 mg 約5 days ¥ 927,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.
Species Human
Expression Host HEK293 Cells
Tag C-hFc
Accession Number Q12864
別名 CDH16, P130, MGC142024, Cdh17, FLJ26931, Cadherin-17, MGC138218, cadherin-16, HPT-1, LI-cadherin, BILL-cadherin
Construction Ala668-Gly777
Protein Purity > 95% as determined by Tris-Bis PAGE
分子量 38.42 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

参考文献

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Keywords

CDH17 Domain 7 Protein, Human, Recombinant (hFc) FLJ-26931 MGC-142024 CDH16 CDH 16 MGC 138218 P130 FLJ 26931 P-130 CDH-16 HPT1 MGC142024 Cdh17 HPT 1 P 130 FLJ26931 MGC-138218 Cadherin-17 MGC138218 MGC 142024 cadherin-16 HPT-1 LI-cadherin BILL-cadherin recombinant recombinant-proteins proteins protein