Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 139,000 |
500 μg | 約5 days | ¥ 555,500 |
1 mg | 約5 days | ¥ 927,500 |
説明 | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-hFc |
Accession Number | Q12864 |
別名 | CDH16, P130, MGC142024, Cdh17, FLJ26931, Cadherin-17, MGC138218, cadherin-16, HPT-1, LI-cadherin, BILL-cadherin |
Construction | Ala668-Gly777 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
分子量 | 38.42 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0). |
Stability & Storage |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CDH17 Domain 7 Protein, Human, Recombinant (hFc) FLJ-26931 MGC-142024 CDH16 CDH 16 MGC 138218 P130 FLJ 26931 P-130 CDH-16 HPT1 MGC142024 Cdh17 HPT 1 P 130 FLJ26931 MGC-138218 Cadherin-17 MGC138218 MGC 142024 cadherin-16 HPT-1 LI-cadherin BILL-cadherin recombinant recombinant-proteins proteins protein